Osteomyelitis bone infection wound care
Condition We Treat · San Antonio

OsteomyelitisBone InfectionTreatment San Antonio

Osteomyelitis is a serious bone infection that may develop from a chronic wound, diabetic foot ulcer, surgery, trauma, or another source of infection. At Hill Country Wound Care & Hyperbarics, our physician-led team helps evaluate suspected bone infections, coordinate diagnostic testing and antibiotic care, support wound healing, and provide adjunctive HBOT for chronic refractory osteomyelitis when medically appropriate.

HBOT-Certified PhysiciansMedicare AcceptedInfectious Disease CoordinationSeen Within 48 Hours
Why It Matters

Osteomyelitis Is Serious.It Requires Specialist Care.

Osteomyelitis develops when bacteria from a chronic wound reach underlying bone — where poor blood supply and an absent immune response allow infection to take hold and persist despite standard antibiotic courses.

Once bone is infected, the wound above it cannot close. Without removing infected bone, controlling the organism with prolonged targeted antibiotics, and restoring oxygen to avascular tissue with HBOT, osteomyelitis almost always recurs — and amputation risk climbs significantly with each recurrence.

Warning Signs

Don't wait — seek specialist care

Deep bone pain or tenderness that is out of proportion to the visible wound
Persistent fever, chills, or fatigue alongside a non-healing wound
A wound that probes to bone or has visible bone at its base
Foul-smelling drainage that won't resolve despite antibiotic treatment
A draining sinus tract — a tunnel through skin that keeps reopening
A wound that is deep, worsening, exposes bone, or is not improving as expected
Your Healing Plan

Your Personalized Osteomyelitis Healing Plan

01

Advanced Diagnostic Workup

We assess the wound, review symptoms and risk factors, and coordinate appropriate testing such as labs, imaging, and tissue or bone cultures when needed to confirm the diagnosis and guide treatment.

02

Targeted Antibiotic Therapy

Antibiotic treatment should be guided by the suspected or confirmed organism, infection severity, culture results, and the patient's overall health. Our team coordinates antibiotic care with the appropriate medical specialists when needed.

03

Surgical Debridement Coordination

When infected or nonviable bone or tissue is present, we coordinate with surgical specialists to determine whether debridement, drainage, bone resection, or another procedure may be needed.

04

Advanced Wound Management

After surgical debridement, we manage the resulting wound with precision — selecting moisture-balanced antimicrobial dressings, negative pressure wound therapy (NPWT), and staged closure techniques tailored to the depth and complexity of the defect.

05

Hyperbaric Oxygen Therapy (HBOT)

For chronic refractory osteomyelitis that has not responded to conventional medical and surgical treatment, HBOT may be added as an adjunct therapy. HBOT helps increase oxygen delivery to infected bone, supports immune cell function, may enhance antibiotic activity, and can support healing as part of a broader physician-directed plan.

06

Biologic & Cellular Tissue Products

Once infection is controlled and the wound bed is appropriate, cellular and tissue-based products may be considered to support soft-tissue closure in select non-healing wounds.

07

Multidisciplinary Collaboration

Osteomyelitis treatment requires a team. We coordinate with orthopedic surgeons, infectious disease specialists, vascular surgeons, and your primary care provider — ensuring every aspect of your care is aligned and progressing toward healing.

Why Hill Country

San Antonio's Largest
Physician-Led Wound Care Network

From board-certified hyperbaric physicians to surgical coordination and three convenient locations, we deliver comprehensive, evidence-based osteomyelitis care — at a fraction of hospital costs.

01

Largest Private, Physician-Led Network

San Antonio's most extensive private outpatient wound care & hyperbarics network, led by board-certified physicians.

02

HBOT-Certified Physicians

Our board-certified hyperbaric physicians are experienced in the adjunctive HBOT protocols for refractory osteomyelitis — a specialized and underutilized treatment option.

03

Three Convenient Locations

Advanced Healing Centers in North, East, and Southwest San Antonio — with easy parking and convenient hours.

04

Affordable Outpatient Model

We accept Medicare and most major insurances. Our outpatient setup keeps your out-of-pocket costs lower than hospital-based programs.

Ready to start your healing journey? Our team is here to help.

Osteomyelitis FAQs

Have more questions? Visit our full FAQ page or explore our articles.

Greater San Antonio

Concerned About a Bone Infection?

Osteomyelitis requires immediate specialist-level evaluation. Get expert care at any of our three San Antonio locations — most patients are seen within 48 hours.

Osteomyelitis (Bone Infection) Treatment in San Antonio, TX

Hill Country Wound Care provides physician-led, multidisciplinary care for osteomyelitis in San Antonio, TX. Our board-certified specialists manage complex bone infections arising from diabetic foot ulcers, pressure injuries, trauma, and post-surgical complications. Our comprehensive approach combines coordination for surgical debridement, long-term targeted antibiotic therapy, and adjunctive Hyperbaric Oxygen Therapy (HBOT) for chronic refractory osteomyelitis, with a primary goal of limb salvage and preventing recurrence.

Understanding Osteomyelitis

Osteomyelitis is a serious infection of the bone. In wound care, it most often occurs via contiguous spread, where bacteria from a chronic, deep wound invade the underlying bone. The compromised blood supply in infected bone makes it difficult for the body's immune system and standard oral antibiotics to reach and eradicate the infection. This is why a combined approach of surgical removal of infected bone, long-term IV antibiotics, and therapies to improve oxygenation like HBOT is often necessary.

Our Treatment Protocol for Osteomyelitis

Our treatment is a coordinated, multi-pronged attack on the infection. 1) Diagnosis: We coordinate advanced imaging (MRI) and bone biopsy to confirm the diagnosis and identify the specific bacteria. 2) Surgical Debridement Coordination: We work with orthopedic or podiatric surgeons to plan for the removal of all infected and non-viable bone. 3) Infectious Disease Coordination: We collaborate with infectious disease specialists to manage the 4-6 week (or longer) course of targeted IV antibiotic therapy. 4) Advanced Wound Care: Post-debridement, we manage the complex surgical wound with NPWT and advanced dressings to achieve closure. 5) Adjunctive HBOT: For chronic, refractory cases, we provide HBOT to enhance oxygen delivery to the bone, improve antibiotic efficacy, and stimulate healing.

Hyperbaric Oxygen Therapy for Chronic Refractory Osteomyelitis

HBOT is a UHMS and Medicare-approved adjunctive therapy for chronic refractory osteomyelitis. By having patients breathe 100% oxygen in a pressurized chamber, we increase the amount of oxygen dissolved in the blood up to 15-fold. This hyper-oxygenated blood reaches the poorly vascularized infected bone, enhancing the killing ability of white blood cells, improving the efficacy of certain antibiotics, and stimulating the growth of new blood vessels to aid healing. HBOT is a critical tool that has been shown to improve resolution rates and reduce amputation risk in complex cases.